Features of clinical manifestations of gonarthritis in women with hypertension and overweight

Authors

  • I. M. Fushtey State institution "Zaporizhia Medical Academy of Post-Graduate Education Ministry of Health of Ukraine", Ukraine
  • A. M. Pidlubna State institution "Zaporizhia Medical Academy of Post-Graduate Education Ministry of Health of Ukraine", Ukraine

DOI:

https://doi.org/10.34287/MMT.1(48).2021.9

Abstract

Abstract One of the diseases that is quite common in modern rheumatology and leads to dysfunction of the musculoskeletal system and creates a major medical and social problem, is gonarthrosis. The incidence of degenerative-dystrophic diseases in HA in women is two to four times higher than in men. In order to establish the patterns of clinical manifestations of GA in women with hypertension (GC) and overweight (HB) of the body, on the basis of the rheumatology department of the city KNP «City Hospital №10» ZMR (Zaporozhye), with informed consent, was prospectively examined 198 women for the period 2018–2020. According to the results of the study, a significant (p <0.05) deterioration of clinical symptoms in women with a combined course of HA with GC and HB, relative to the isolated course of HA, on the indicators: pain during active and passive movements and palpation, stiffness, crepitation and swelling of the joints. The correlations between clinical manifestations of HA, arthrosonographic data and BMI have been established. The characteristics of the pain syndrome associated with exercise, impaired mobility and functionality of the joints significantly increased with increasing stage of GA, joining comorbid pathology and increased BMI.

References

Belyalov FI, Lechenie vnutrennih bolezney v usloviyah komorbidnosti. Irkutsk;2011. 305 p.

EULAR Compendium on Rheumatic Disease. Ed. JWJ Bijsma; 2009 BMJ. 824 p.

Reid JL, Morton DJ, Wingard DD.et al. Obesity and other cardiovascular disease risk factors and their association with osteoarthritis in Southern California American IndiansEthn. Dis. – 2010;20 (4):416–422.

GalyutIna OYu, StanIslavchuk MA, DislIpIdemIya u patsIEntIv Iz revmatoYidnim artritom I YiYi zv’yazok z osoblivostyami perebIgu zahvoryuvannya.Ukr. revmatologIch. zhurn. 2007;1(27)8–12.

Asokan G, Hussain MS, Ali EJ et al.Osteoarthritis among women in bahrain: a public health audit.Oman. Med. J.-2011;26 (6):426–430.

Baraf HS, Gold MS, Petruschke RA. et al. Tolerability of topical diclofenac sodium 1% gel for osteoarthritis in seniors and patients with comorbidities.Am. J. Geriatr. Pharmacother. 2012;10 (1) 47–60.

Tkachenko MV. PatogenetichnI mehanIzmi rozvitku deformIvnogo osteoartrozu u poednannI z metabolIchnim sindromom.Ukr. revmatologIch. zhurn. 2009; 4 (38):86–88.

Whelton A, Gibofsky A. Minimizing cardiovascular complications during the treatment of osteoarthritis.Am. J. Ther. 2011;18(6):466–476.

Romanova IA. Kliniko-diagnosticheskoe znachenie endotelialnoy disfunktsii i ee medikamentoznaya korrektsiya u bolnyih osteoartrozom[ dis. kand. med. Nauk] Saratov;2009. 129 p.

Puenpatom RA, Victor TW. Increased prevalence of metabolic syndrome in individuals with osteoarthritis: an analysis of NHANES III data.Postgrad. Med. 2009; 121 (6):9–20.

Denisov LN, Nasonova VA, Koreshkov GG. et al.Role of obesity in the development of osteoarthrosis and concomitant diseases.Ter. Arkh. 2010;82(10):34–37.

Leite AA, Costa AJ, Lima BA et al. Comorbidities in patients with osteoarthritis: frequency and impact on pain and physical function.Rev. Bras. Reumatol. 2011;51(2):118–123.

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Published

2021-04-20

How to Cite

Fushtey, I. M. ., & Pidlubna, A. M. . (2021). Features of clinical manifestations of gonarthritis in women with hypertension and overweight. Modern Medical Technology, (1), 53–58. https://doi.org/10.34287/MMT.1(48).2021.9

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Original research