Diagnosis and treatment of destructive forms of acute pancreatitis

Authors

  • V. V. Mishchenko Odessa National Medical University, Department of Surgery № 1 Odessa, Ukraine, Ukraine
  • V. V. Hrubnyk Odessa National Medical University, Department of Surgery № 1 Odessa, Ukraine, Ukraine
  • P. I. Pustovoyt Odessa Regional Clinical Hospital Odessa, Ukraine, Ukraine
  • V. V. Horyachyy Odessa Region State Administration Odessa, Ukraine, Ukraine
  • V. V. Velychko Odessa Regional Clinical Hospital Odessa, Ukraine, Ukraine
  • R. Yu. Vododyuk Odessa Regional Clinical Hospital Odessa, Ukraine, Ukraine

DOI:

https://doi.org/10.34287/MMT.2(41).2019.13

Abstract

Purpose of the study. The study of the diagnosis and treatment of destructive forms of acute pancreatitis and the identification of possible ways to optimize them.

Materials and methods. Destructive forms of acute pancreatitis were found in 16,8%. The algorithm for treating acute destructive pancreatitis consisted in artificial ventilation of the lungs, adequate infusion therapy, peridural anesthesia, setting up a nasoenteric probe, stimulating the bowels, correcting hemodynamics, intraand extracorporal detoxification, antisecretory, anti-bacterial, hepatoprotective, cerebroprotective, antioxidant therapy, directed immune correction, use of anti-enzyme drugs, suppression of the release of mediators inflammation, external secretory activity of the pancreas. Medical video laparoscopy and puncture interventions under the control of ultrasound were used as the first stage of surgical treatment. The indications for traditional surgical interventions are large areas of aseptic destruction, unlimited infected pancreatic necrosis, infection of necrotic areas with complete cell sequestration, abscesses with large sequesters, abdominal phlegmon, signs of progressive multiple organ failure and the development of arousal hemorrhage, perforation of cystic formations in the abdominal cavity, perforation of a hollow organ, purulent peritonitis.

Results. The developed therapeutic tactics allowed, in destructive forms of acute pancreatitis, to achieve a reduction in overall mortality to 23,4%.

Conclusion. Diagnostic and treatment tactics for destructive forms of acute pancreatitis should be standardized depending on the timing, severity of the disease, localization and prevalence of the destructive process, systemic and local complications.

References

Bagnenko SF, Goltsov VR. Acute pancreatitis is the current state of the problem and unresolved issues. Almanakh instituta khirurgii im. AV Vishnevskogo. 2008; 3 (3): 104–112.

Kaliev AA. Analysis of deaths of patients with destructive forms of acute pancreatitis. Sovremennyye problemy nauki i obrazovaniya. 2013; 5: 32–37.

Casas JD et al. Prognostic Value of CT in Patients with Acute Pancreatitis. Am J Gastroenterol. 2004; 182: 569–574. DOI: 10.2214/ajr.182.3.1820569

Kubyshkin VA, Moroz OV, Stepanova YuA et al. Issues of classification of acute pancreatitis. Annaly khirurgicheskoy gepatologii. 2012; 17 (2): 86.

Aleksandrovich YuS. Evaluation and prognostic scales in medicine of critical conditions. 2-ye izd.,dop. i ispr. SPb: ELBI–SPb. 2010, pp. 29–36.

Shapovalyants SG, Mylnikov AG, Pankov AG. Surgical interventions in acute necrotising pancreatitis. Annaly khirurgicheskoy gepatologii. 2010; 15 (2): 58–65.

Korotkov NI, Kukushkin AV, Metelev AS. Miniinvasive technologies in the diagnosis and treatment of local purulent complications of destructive pancreatiti. Khirurgiya. 2005; 3: 40–44.

Ermolov AS, Borovkova NV, Ivanov PA et al. Immunological assessment of severity and prognosis of acute pancreatitis. Vestnik khirurgii im II Grecova. 2005; 164 (6): 22–28.

Dyuzheva TG, Dzhus EV, Shefer AV et al. Configuration of pancreatic necrosis and differentiated treatment of acute pancreatitis. Annaly khirurgicheskoy gepatologii. 2013; 18 (1): 92–102.

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Published

2019-06-20

How to Cite

Mishchenko, V. V. ., Hrubnyk, V. V. ., Pustovoyt, P. I. ., Horyachyy, V. V. ., Velychko, V. V. ., & Vododyuk, R. Y. . (2019). Diagnosis and treatment of destructive forms of acute pancreatitis. Modern Medical Technology, (2), 65–70. https://doi.org/10.34287/MMT.2(41).2019.13