Stress-induced diseases of the thyroid gland in Ukraine during hostilities
DOI:
https://doi.org/10.34287/MMT.3(58).2023.5Abstract
The aim of the study: to analyze and evaluate the relationship between previous life events of a stressful nature in patients who have surgical diseases of the thyroid gland.
Materials and methods. We used the questionnaire method (The Life Experiences Survey Irwin G. Sarason, 1978) of patients before planned surgical intervention on the thyroid gland. The number of positive and negative events that happened to patients during the previous year was evaluated.
Results. Among individuals, significantly more adverse events were reported by patients with Graves’ disease (128.0 ± 2.3 points) and proliferative hyperthyroid nodular goiter (105.0 ± 1.7 points) compared to patients treated surgically for euthyroid nodular goiter (53.0 ± 0.7 points of negative events) and thyroid carcinomas (62.0 ± 0.8 points of negative events).
Conclusions. It has been proven that stress and negative life events can be triggers for dysfunction and development of thyroid gland diseases.
Analysis of a patient survey before thyroid surgery indicated a possible relationship between acute stress and the initiation of Graves’ disease and proliferative hyperthyroid nodular goiter.
References
Usenko OY, Khomenko IP, Kovalenko AE, Saliutin RV. [Stress and surgical diseases of thyroid gland in environment of the armed conflict (review of literature and own observations)]. Klinicheskaia khirurgiia. 2022;89(3-4):73-80. doi: 10.26779/2522-1396.2022.3-4.73.
Fukao A, Takamatsu J, Arishima T, Tanaka M, Kawai T, Okamoto Y, et al. Graves’ disease and mental disorders. J Clin Transl Endocrinol. 2019;19:100207. doi: 10.1016/j.jcte.2019.100207.
Paunkovic N, Paunkovic J, Pavlovic O, Paunovic Z. The significant increase in incidence of Graves’ disease in eastern Serbia during the civil war in the former Yugoslavia (1992 to 1995). Thyroid. 1998;8(1):37-41. doi: 10.1089/ thy.1998.8.37.
Usenko OY, Khomenko IP, Kovalenko AY, Halochka IP, Andreieshchev SA, Saliutin RV, et al. [Surgical management of thyroid disease Clinical and practical recommendations]. Klinicheskaia khirurgiia. 2022;89(9-10):41-82. doi: 10.26779/2522-1396.2022.9-10.41.
Sarason IG, Levine HM, Basham RB, Sarason BR. Assessing social support: The Social Support Questionnaire. J Pers Soc Psychol. 1983;44(1):127-39. doi: 10.1037/0022-3514.44.1.127.
Kyriacou A, Tziaferi V, Toumba M. Stress, Thyroid Dysregulation, and Thyroid Cancer in Children and Adolescents: Proposed Impending Mecha- nisms. Horm Res Paediatr. 2023;96(1):44-53. doi: 10.1159/000524477.
Barajas Galindo DE, Ramos Bachiller B, González Roza L, García Ruiz de Morales JM, Sánchez Lasheras F, González Arnáiz E, et al. Increased incidence of Graves’ disease during the SARS-CoV2 pandemic. Clin Endocrinol (Oxf). 2023;98(5):730-7. doi: 10.1111/cen.14860.