Experience of urgent surgical thrombolectomy of high-risk acute massive pulmonary embolism under parallel cardiopulmonary bypass: a case report





thrombophilia, deep vein thrombosis, venous thromboembolism, pulmonary hypertension, right ventricular failure, critical hypotension, multispiral computed tomography, Miller index, surgical thrombolysis


Massive acute pulmonary embolism is a rare and life-threatening condition that cardiac surgeons may encounter in their clinical practice. Although systemic thrombolysis is often prescribed in critically ill patients to improve pulmonary perfusion and reduce right ventricular afterload, surgical treatment is an objective alternative when thrombolytic therapy is ineffective or impossible.

Aim. Determining the expediency of pulmonary thromboembolectomy in the case of unavailability or impossibility of systemic thrombolysis to optimize treatment protocols for patients with high-risk pulmonary embolism accompanied by hemodynamic instability.

Materials and methods. We present clinical cases of patients with high-risk pulmonary embolism as determined by multispiral computed tomography with Miller index determination. In both cases, the condition of the patients upon admission was critical, due to rapidly progressing hemodynamic instability, severe pulmonary hypertension, and right ventricular failure.

Results. The patients were urgently brought to the operating room with severe desaturation, bradycardia, in a state of medical sedation and with pronounced hypotension. Taking into account the patients’ severe condition and the results of the tomography, we performed emergency pulmonary thromboembolectomy using a modified surgical technique using cardiopulmonary bypass without deep hypothermia or transverse aorta clamping.

Conclusions. The complete clinical remission resulting from the clinical observations described in this study demonstrates the feasibility of performing open pulmonary thromboembolectomy in combination with anticoagulant therapy in patients with high-risk pulmonary embolism accompanied by hemodynamic instability based on clinical diagnosis in specific individual cases.

Author Biographies

V. V. Osaulenko, Zaporizhzhia State Medical and Pharmaceutical University, Ukraine

MD, PhD, Associate Professor of the Department of Surgery 1, Educational and Scientific Institute of Postgraduate Education, Ukraine

K. O. Chmul, Zaporizhzhia State Medical and Pharmaceutical University, Ukraine

MD, PhD, Assistant of the Department of Hospital Surgery, Zaporizhzhia State Medical and Pharmaceutical University, Ukraine

R. I. Budaghov, Zaporizhzhia State Medical and Pharmaceutical University, Ukraine

Senior Laboratory Assistant of the Department of Hospital Surgery, Zaporizhzhia State Medical and Pharmaceutical University, Ukraine


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How to Cite

Osaulenko, V. V., Chmul, K. O., & Budaghov, R. I. (2024). Experience of urgent surgical thrombolectomy of high-risk acute massive pulmonary embolism under parallel cardiopulmonary bypass: a case report. Modern Medical Technology, 16(2), 152–160. https://doi.org/10.14739/mmt.2024.2.301167