Sagittal profile of knee joint morphotypes in osteoarthritis

Authors

DOI:

https://doi.org/10.14739/mmt.2025.4.335512

Keywords:

knee joint, osteoarthritis, degenerative-dystrophic diseases, gonarthrosis, morphology

Abstract

The aim of the study was to characterize the features of sagittal morphology of knee joints in osteoarthritis, considering the structural variant of the joint determined by our own cluster system.

Materials and methods. A total of 100 knee radiographs from 70 patients diagnosed with osteoarthritis were analyzed. Based on the proposed classification system, morphotype I was identified in 21 patients (21.00 %), morphotype II in 38 (38.00 %), morphotype III in 29 (29.00 %), and morphotype IV in 12 patients (12.00 %). The following radiographic parameters were assessed: posterior distal femoral angle (PDFA), posterior condylar offset ratio (PCOR), posterior tibial slope (PTS), tuberosity-modified tibial slope (TMTS), and tibial tuberosity inflection angle (TTIA). Statistical analysis was performed using Statistica 13 software. Statistical significance was defined at p ≤ 0.05.

Results. The mean PDFA was 84.98 ± 5.62°. Mean values across morphotypes were: morphotype I – 89.27 ± 1.79°, morphotype II – 87.20 ± 4.50°, morphotype III – 83.11 ± 4.33°, and morphotype IV – 75.43 ± 2.64° (p < 0.00001). The mean PCOR was 0.44 ± 0.08. The index value in patients with morphotype I was 0.45 ± 0.05, morphotype II – 0.44 ± 0.10, morphotype III – 0.45 ± 0.07, morphotype IV – 0.39 ± 0.06 (p = 0.14). The mean PTS was 9.00 ± 4.18°. The highest values were found in patients with morphotype I – 11.82 ± 4.00°, patients with morphotype II – 9.72 ± 4.72°, morphotype III – 7.58 ± 2.91°, and morphotype IV – 5.86 ± 1.46° (p = 0.01). The average TMTS was 36.48 ± 6.28°. The angle value in patients with morphotype I was 35.36 ± 3.78°, morphotype II – 34.92 ± 7.17°, morphotype III – 37.45 ± 5.78°, morphotype IV – 41.14 ± 5.52° (p = 0.045). The mean TTIA was 160.54 ± 6.81°: in individuals with morphotype I – 157.91 ± 8.81°, morphotype II – 158.62 ± 5.90°, morphotype III – 162.74 ± 6.07°, and morphotype IV – 165.57 ± 4.31° (p = 0.008). A significantly higher likelihood of morphotype III was observed in patients with PDFA values 79–87° (OR = 5.66, 95 % CI: 1.71–18.68, p = 0.003). A higher probability of morphotype II development was associated with PCOR values >0.44 (OR = 3.34, 95 % CI: 1.06–10.50, p = 0.03). The presence of PTS values > 8° increases the odds of morphotype I formation (OR = 6.43, 95 % CI: 1.22–33.95, p = 0.01).

Conclusions. Given the identified morphotype-specific differences in sagittal knee joint morphology in osteoarthritis, further studies are needed to justify a personalized approach to orthopaedic surgical planning.

Author Biographies

R. I. Blonskyi, Institute of Traumatology and Orthopedics of the National Academy of Medical Sciences of Ukraine

MD PhD, DSc, Senior Researcher at the Clinic of Sports and Ballet Injuries, SI “Institute of Traumatology and Orthopedics of the National Academy of Medical Sciences of Ukraine”; Professor of Surgery Department No. 2, Private Higher Educational Establishment “Kyiv Medical University”, Orthopedic and Trauma Surgeon of the highest qualification category, Kyiv

L. O. Kylymniuk, Medical Centre “Angels Clinic”, Vinnytsia

MD, PhD, Orthopedic and Trauma Surgeon

References

Giorgino R, Albano D, Fusco S, Peretti GM, Mangiavini L, Messina C. Knee Osteoarthritis: Epidemiology, Pathogenesis, and Mesenchymal Stem Cells: What Else Is New? An Update. Int J Mol Sci. 2023;24(7):6405. doi: https://doi.org/10.3390/ijms24076405

Jang S, Lee K, Ju JH. Recent Updates of Diagnosis, Pathophysiology, and Treatment on Osteoarthritis of the Knee. Int J Mol Sci. 2021;22(5):2619. doi: https://doi.org/10.3390/ijms22052619

Primorac D, Molnar V, Rod E, Jeleč Ž, Čukelj F, Matišić V, et al. Knee Osteoarthritis: A Review of Pathogenesis and State-Of-The-Art Non-Operative Therapeutic Considerations. Genes (Basel). 2020;11(8):854. doi: https://doi.org/10.3390/genes11080854

Wang Y, Lu J, Wang Z, Li Z, Pan F, Zhang M, et al. The association between patella alignment and morphology and knee osteoarthritis. J Orthop Surg Res. 2024;19(1):509. doi: https://doi.org/10.1186/s13018-024-05001-6

Lv Y, Sui L, Lv H, Zheng J, Feng H, Jing F. Burden of knee osteoarthritis in China and globally from 1992 to 2021, and projections to 2030: a systematic analysis from the Global Burden of Disease Study 2021. Front. Public Health. 2025;13:1543180. doi: https://doi.org/10.3389/fpubh.2025.1543180

Lee SH, Yoo JH, Kwak DK, Kim SH, Chae SK, Moon HS. The posterior tibial slope affects the measurement reliability regarding the radiographic parameter of the knee. BMC musculoskeletal disorders. 2024;25(1):202. doi: https://doi.org/10.1186/s12891-024-07330-3

Handa M, Takahashi T, Saitsu A, Iguchi M, Takeshita K. Comparison of coronal and sagittal alignment in patients without osteoarthritis but with knee complaints. J Exp Orthop. 2025;12(1):e70165. doi: https://doi.org/10.1002/jeo2.70165

Meier M, Janssen D, Koeck FX, Thienpont E, Beckmann J, Best R. Variations in medial and lateral slope and medial proximal tibial angle. Knee surgery, sports traumatology, arthroscopy. 2021;29(3);939-46. doi: https://doi.org/10.1007/s00167-020-06052-y

Siddiqi A, Anis H, Borukhov I, Piuzzi NS. Osseous Morphological Differences in Knee Osteoarthritis. J Bone Joint Surg Am. 2022;104(9):805-12. doi: https://doi.org/10.2106/JBJS.21.00892

Kylymniuk LO, Matsipura MM, Iaremyn SI. Clustering of knee joint types affected by the degenerative-dystrophic process. Ukrainian Medical Journal. 2025; (2):117-22. doi: https://doi.org/10.32471/umj.1680-3051.264438

Kylymniuk L, Matsipura M, Iaremyn S. [Variations in patellar position according to knee joint morphotype in patients with osteoarthritis]. Pain, joints, spine. 2025;15(2):61-9. Ukrainian. doi: https://doi.org/10.22141/pjs.15.2.2025.462

Abalkhail TB, McClure PK. Sagittal Plane Assessment in Deformity Correction Planning: The Sagittal Joint Line Angle. Strategies Trauma Limb Reconstr. 2022;17(3):159-64. doi: https://doi.org/10.5005/jp-journals-10080-1569

Cassar-Pullicino VN, Davies AM, editors. Measurements in musculoskeletal radiology. Berlin, Germany: Springer; 2020. doi: https://doi.org/10.1007/978-3-540-68897-6

The World Medical Association. (1964/2013). Declaration of Helsinki: Ethical Principles for Medical Research Involving Human Subjects [Internet]. Ferney-Voltaire: WMA; 2013 [cited 2025 Jun 9]. Available from: https://www.wma.net/what-we-do/medical-ethics/declaration-of-helsinki/

Council of Europe. Konventsiia pro zakhyst prav liudyny ta hidnosti liudyny shchodo zastosuvannia biolohii ta medytsyny: Konventsiia pro prava liudyny ta biomedytsynu [Convention for the protection of human rights and dignity of the human being with regard to the application of biology and medicine: convention on human rights and biomedicine] [Internet]. Strasbourg: Council of Europe; 1997 [cited 2025 Jul 9]. Available from: https://zakon.rada.gov.ua/laws/show/994_334#Text

Ministry of Health of Ukraine. Pro zatverdzhennia poriadku provedennia klinichnykh vyprobuvan likarskykh zasobiv ta ekspertyzy materialiv klinichnykh vyprobuvan ta typovoho polozhennia pro etychni komitety [On approval of the procedure for conducting clinical trials of medicinal products and examination of clinical trial materials and model regulation on ethics committees]. Order dated 2009 Sep 23, No. 690. Available from: https://zakon.rada.gov.ua/laws/show/z1010-09#Text

Yang D, Zhou Y, Shao H, Deng W. Different Deformity Origins and Morphological Features in Subtypes of Valgus Knees: A Radiological Classification System. Orthop Surg. 2022;14(1):96-103. doi: https://doi.org/10.1111/os.13178

Xin L, Xingjia M, Shengjie G, Yanwei C, Shuaijie L, Chuan X. Comparison of Tibial Tubercle Landmark Technique and Range of Motion Technique in Primary Total Knee Arthroplasty: A Retrospective Cohort Study. Orthop Surg. 2022;14(12):3159-70. doi: https://doi.org/10.1111/os.13486

Saidapur SK, Sai Srinivas P, Shete S, Hundekar A, Jatti RS. Radiological assessment of the posterior tibial slope as a risk factor for osteoarthritis of the knee in Indian population. Trends Clin Med Sci. 2023;3(Spec Iss 2):397-402. Available from: https://pisrt.org/psrpress/j/tcms/2023/special-issue-2/radiological-assessment-of-the-posterior-tibial-slope-as-a-risk-factor-for-osteoarthritis-of-the-knee-in-indian-population.pdf

Wu Y, Lu W, Li Z, Xie H, Tang L, Pan E. [Analysis of the influence of tibial component posterior slope angle on short- and mid-term effectiveness of unicompartmental knee arthroplasty]. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2022;36(2):189-95. Chinese. doi: https://doi.org/10.7507/1002-1892.202110019

Hohmann E, Nel A, Zyl RV, Keough N, Mogale N. A morphometric study of posterior tibial slope differences by sex and ethnicity in a South African population. Surg Radiol Anat. 2025;47(1):52. doi: https://doi.org/10.1007/s00276-024-03551-2. Erratum in: Surg Radiol Anat. 2025;47(1):130. doi: https://doi.org/10.1007/s00276-025-03639-3

Hiranaka Y, Muratsu H, Tsubosaka M, Matsumoto T, Maruo A, Miya H, et al. Influence of posterior tibial slope on sagittal knee alignment with comparing contralateral knees of anterior cruciate ligament injured patients to healthy knees. Sci Rep. 2022;12(1):14071. doi: https://doi.org/10.1038/s41598-022-18442-y

Mas Matas B, Barberà IC, Marsico S, Claramunt AA, Torres-Claramunt R, Solano López A. Importance of posterior tibial slope, medial tibial plateau slope and lateral tibial plateau slope in anterior cruciate ligament injury. Open J Orthop. 2021;11(9):233-48. doi: https://doi.org/10.4236/ojo.2021.119022

Dean RS, Beck EC, Waterman BR. Knee malalignment: Is there a role for correction in primary ACLR? Oper Tech Sports Med. 2021;29(2):150833. doi: https://doi.org/10.1016/j.otsm.2021.150833

Chen Y, Ding J, Dai S, Yang J, Wang M, Tian T, et al. Radiographic measurement of the posterior tibial slope in normal Chinese adults: a retrospective cohort study. BMC Musculoskelet Disord. 2022;23(1):386. doi: https://doi.org/10.1186/s12891-022-05319-4

Springer B, Waldstein W, Bechler U, Jungwirth-Weinberger A, Windhager R, Boettner F. The Functional Status of the ACL in Varus OA of the Knee: The Association With Varus Deformity and Coronal Tibiofemoral Subluxation. The Journal of arthroplasty. 2021;36(2):501-6. doi: https://doi.org/10.1016/j.arth.2020.08.049

Additional Files

Published

2025-12-25

How to Cite

Blonskyi, R. I., & Kylymniuk, L. O. (2025). Sagittal profile of knee joint morphotypes in osteoarthritis. Modern Medical Technology, 17(4), 279–290. https://doi.org/10.14739/mmt.2025.4.335512